Transformation of Developmental Neurotoxicity Data into a Struct...

Courtesy Recent Science Inventory records from the EPA  Mon, 12/21/2009 - 14:02

A database of neurotoxicants is critical to support the development and validation of animal alternatives for neurotoxicity.

Validation of in vitro test methods can only be done using known animal and human neurotoxicants producing defined responses for neurochemical, neuropathological, and neurobehavioral endpoints.

Consequently, the development of a neurotoxicity database is an important step in the development of neurotoxicity animal alternatives.

A working group was formed to construct a publicly available, structure-searchable database to increase the understanding of relationships between chemical...

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