breast cancer cells

Isolated Breast Cancer Cells In Sentinel Lymph Node Associated W...

admin — Fri, 21 Nov 2008 18:00:10 -0600

Women who are found to have isolated breast cancer cells upon sentinel lymph node biopsy have a risk of having metastases in other lymph nodes.

Cancer Drug Resistance: 'New' Estrogen Receptor Found To Be Key ...

admin — Thu, 30 Oct 2008 11:15:08 -0500

Researchers have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world's largest-selling breast cancer prevention and treatment drug. They say the findings could provide a way to identify tamoxifen users who are no longer benefiting from the drug, allowing doctors to try another therapy option sooner.

Breast Cancer Cells Recycle To Escape Death By Hormonal Therapy

admin — Sun, 05 Oct 2008 02:30:05 -0500

Many breast cancer cells facing potentially lethal antiestrogen therapy recycle to survive, researchers say.

Team discovers new inhibitors of estrogen-dependent breast cance...

admin — Mon, 16 Jun 2008 00:00:00 -0500

(University of Illinois at Urbana-Champaign) Researchers have discovered a new family of agents that inhibit the growth of estrogen-dependent breast cancer cells. The finding, described today at a meeting of the Endocrine Society, has opened an avenue of research into new drugs to combat estrogen-dependent breast cancers.

Previously Unseen Switch Regulates Breast Cancer Response To Est...

admin — Fri, 09 May 2008 14:45:25 -0500

A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells. Most breast cancers contain estrogen receptors, which enable them to grow in the presence of the hormone estrogen. Their presence can determine whether tumors will respond to the estrogen-blocking drug tamoxifen. The finding will help researchers sort out how mutations change the estrogen receptor's function and allow some breast cancers to resist tamoxifen.

Predicting Breast Cancer Patient Outcome: New Genes Identified

admin — Mon, 28 Apr 2008 00:00:00 -0500

The environment surrounding breast cancer cells plays a crucial role in determining whether tumor cells grow and migrate or whether they fade away. A new study is the first to identify the genes behind this environmental control and correlate them with patient outcome.

Common Organic Compound Found In Many Household Products May Pos...

admin — Thu, 03 Apr 2008 11:00:00 -0500

Bisphenol A, a chemical that leaches into food and beverages from many consumer products, causes normal, non-cancerous human breast cells to express genes characteristic of aggressive breast cancer cells. The concentration of BPA that the researchers tested was very low (less than one tenth of a millionth of a gram per milliliter), but this concentration of BPA has been found in blood from pregnant women in both the United States and Germany.

New revelations in epigenetic control shed light on breast cance...

admin — Tue, 04 Mar 2008 23:00:00 -0600

Epigenetic regulation -- modifications to the structure of chromatin that influence which genes are expressed in a cell -- is a key player in embryonic development and cancer formation. Researchers at the European Molecular Biology Laboratory in Heidelberg now gained new insight into one crucial epigenetic mechanism and reveal that it acts much faster than assumed. In this week's issue of Nature they report that estrogen causes rapid epigenetic changes in breast cancer cells.