Small changes in protein chemistry play large role in Huntington...

Courtesy EurekAlert! - Chemistry, Physics and Materials Sciences  Wed, 12/23/2009 - 23:00

(NIH/National Institute of Neurological Disorders and Stroke) Investigators studying the toxic protein at the root of Huntington's disease have found that small biochemical changes to the protein have a large effect on its toxicity.

These changes could be exploited or mimicked to develop a drug treatment for Huntington's. The findings appear in two new studies supported by the National Institutes of Health.

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