viral vector

Safer Gene Therapy May Be Possible Using Novel Approach

ScienceDaily  Fri, 03/21/2008 - 19:00

A novel strategy for circumventing safety problems that have plagued gene therapy has been offered by a complex multicenter group of researchers.

The study reports that adenovirus type 5, a common vector for delivering gene therapy, transfects liver cells by a different mechanism than previously thought.

That mechanism offers a new target for modifying the viral vector to make it safe for clinical use.