molecule

Scientists at UT Southwestern Medical Center have found a potential new way to stop the bacteria that cause gastroenteritis, tularemia and severe diarrhea from making people sick.

Scientists have identified a way to "switch off" a molecule, a key player in the molecular processes that trigger breast cancer and certain forms of leukaemia.

(Whitehead Institute for Biomedical Research) Embryonic-like stem cells can be efficiently generated using a natural signaling molecule instead of the virally delivered cancer-causing gene c-Myc.The results represent progress in overcoming hurdles to the potential use of reprogrammed cells for stem-cell-based therapies in humans.

Our bodies rely on the production of potent, or 'high affinity,' antibodies to fight infection. The process is very complex, yet scientists have discovered that it hinges on a single molecule, a growth factor, without which it cannot function.

A small molecule that locks an essential enzyme in an inactive form could one day form the basis of a new class of unbeatable, species-specific drugs, including antibiotics.

PBGS, an enzyme used by nearly all cellular life, is a morpheein -- a molecule that spontaneously "shape-shifts," -- turning from an active octamer (eight part) protein to a hexamer (six part).

Morphlock stabilizes the hexamer, thereby turning off the enzyme.

An Australian research project has found a way to bring forward the detection of early stage Alzheimer's disease by up to 18 months.

Alzheimer’s disease is characterized by very high levels of a molecule called beta-amyloid in the brain.

Inspired by a chance discovery during another experiment, researchers have created a small molecule that stimulates nerve stem cells to begin maturing into nerve cells in culture.

Scientists have discovered an unknown regulator of fat and cholesterol production in the liver of mice, a significant finding that could lead to new therapies for lowering unhealthy blood levels of cholesterol and fats.

(Stanford University) Proteins, long and linear when first made, must fold into specific configurations before they can properly do their job in a cell.

How they are folded is a mystery, but Stanford researcher Judith Frydman has begun prying the lid off a type of molecule called a chaperonin, which folds some of the most essential proteins for life.

Her goal is to control protein folding, which has therapy implications for many diseases caused by misfolding.

A new study identifies a signaling molecule that plays a major role in radiation-induced intestinal damage.

The research may lead to new strategies for protecting normal tissues from radiation during cancer therapies.