genetic variant

Gene That Regulates Glucose Levels And Increases Risk For Diabet...

ScienceDaily  Mon, 06/09/2008 - 18:15

Researchers have identify a genetic variant that regulates glucose levels and also increases the risk of type 2 diabetes.


 

Genetic variant mimics effect of heart failure medications

EurekAlert! - Chemistry, Physics and Materials Sciences  Sat, 04/19/2008 - 23:00

A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected.

Researchers found that the genetic variation acts just like beta-blockers, a class of drugs used to treat chronic heart failure.

The researchers say their discovery adds to the accumulating evidence that genetic differences contribute to the way people respond to medications.


 

Many African-Americans Have A Gene That Prolongs Life After Hear...

ScienceDaily  Sat, 04/19/2008 - 23:00

About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to new research.

The new study offers a reason why beta blockers don't appear to benefit some African-Americans.


 

Genetic Variant Mimics Effect Of Heart Failure Medications

ScienceDaily  Sat, 04/19/2008 - 23:00

A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected.

Researchers found that the genetic variation acts just like beta-blockers, a class of drugs used to treat chronic heart failure.

The researchers say their discovery adds to the accumulating evidence that genetic differences contribute to the way people respond to medications.


 

Complexities Of Genetic Susceptibility To Tuberculosis Revealed

ScienceDaily  Sat, 03/29/2008 - 07:00

Researchers working in Vietnam have identified a genetic variant that predisposes people to developing a lethal form of tuberculosis, tuberculous meningitis, if they are infected with a strain of TB known as the Beijing strain.

The work underlines the importance of studying both sides of the complex host-pathogen interaction and its role in susceptibility to disease.


 

Anchoring Protein Variant Associated with Increased Breast Cance...

ScienceDaily  Fri, 03/14/2008 - 19:00

Individuals who carry a rare genetic variant have an increased risk of developing breast cancer over their lifetimes, compared with those who do not have the variant.

Few genes have been found to have a large impact on the risk of familial breast cancer, and researchers expect that most breast cancers are influenced by the combined effects of multiple genes, each of which has a small impact on its own.

One of those genes may be AKAP9.