gene family

Scientists have sequenced the genome of the chytrid fungus known as Batrachochytrium dendrobatidis. Bd has been a major player in declining frog populations around the world.

The scientists compared gene activation in two stages of Bd's life cycle. Out of several genes identified, one gene family in particular may hold the key to how the fungus kills frogs.

A family of genes linked to the development of liver cancer have been identified. Researchers discovered in a mouse model that the loss of one specific gene (Iqgap2) in this family causes Hepatocellular carcinoma (HCC).

They also found that when another member of the gene family (Iqgap1) is turned on, a more aggressive form of the disease occurs.