drug resistance

Stopping Germs From Ganging Up On Humans

ScienceDaily  Thu, 11/27/2008 - 01:30

Evolutionary theory points to a new approach to combat drug resistance in disease-causing organisms and in cancer, according to new research.

Keeping germs from cooperating can delay the evolution of drug resistance more effectively than killing germs one by one with traditional drugs such as antibiotics.


 

Stopping germs from ganging up on humans

EurekAlert! - Chemistry, Physics and Materials Sciences  Wed, 11/19/2008 - 23:00

(University of Arizona) Evolutionary theory points to a new approach to combat drug resistance in disease-causing organisms and in cancer, according to new research.

Keeping germs from cooperating can delay the evolution of drug resistance more effectively than killing germs one by one with traditional drugs such as antibiotics.


 

Cancer Drug Resistance: 'New' Estrogen Receptor Found To Be Key ...

ScienceDaily  Thu, 10/30/2008 - 10:15

Researchers have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world's largest-selling breast cancer prevention and treatment drug.

They say the findings could provide a way to identify tamoxifen users who are no longer benefiting from the drug, allowing doctors to try another therapy option sooner.


 

Human Protein May Offer Novel Target For Blocking HIV Infection:...

ScienceDaily  Mon, 04/28/2008 - 18:30

A research group has uncovered a new route for attacking the human immunodeficiency virus that may offer a way to circumvent problems with drug resistance.

Researchers have blocked HIV infection in the test tube by inactivating a human protein expressed in key immune cells.


 

Identification Of BCAR Genes Relevant For Breast Cancer Progress...

ScienceDaily  Sat, 04/12/2008 - 23:00

Dutch researchers report identifying a set of seven genes responsible for drug resistance and aggressiveness in the most common form of breast cancer.

These genes, some of which are novel, could provide therapeutic targets for personalized treatment of breast cancer and, possibly, for prevention of disease, they say.

These genes are found in estrogen receptor-positive (ER+) breast cancer, which investigators say is usually more treatable than breast cancer that is not fueled by estrogen.


 

New Approach To Help Control Drug Resistance In Leukemia Identif...

ScienceDaily  Tue, 03/25/2008 - 19:00

Researchers have found that an experimental drug known as SGX393 is effective against Gleevec-resistant chronic myeloid leukemia.

New research gives additional therapeutic tools for even more effective and longer control of chronic myeloid leukemia.


 

Confronting The Challenge Of Antimicrobial Resistance

ScienceDaily  Wed, 03/12/2008 - 04:00

Drug resistance is making many diseases increasingly difficult -- and sometimes impossible -- to treat. In a new report in the Journal of Infectious Diseases, now available online, Dr.

Fauci outlines NIAID's commitment to addressing this urgent public health issue.


 

Microscopic 'Astronauts' To Go Back In Orbit

ScienceDaily  Tue, 03/11/2008 - 10:00

When space shuttle Endeavor blasts off on March 11, some tiny "astronauts" will piggyback onboard an experimental payload of microbes.

A new experiment, called "Microbial Drug Resistance Virulence" is part of the STS-123 space shuttle Endeavor mission.

The experimental payload aboard space shuttle Endeavor will continue studies on the ability of germs to cause disease.


 

Symposium on drug-resistant diseases set for annual AAAS confere...

EurekAlert! - Mathematics and Statistics  Sat, 02/16/2008 - 23:00

Drug resistance is a major public health concern, and the problem of resistance continues to grow. Recently, infectious disease modelers have begun to develop mathematical models for predicting the evolutionary dynamics of drug resistance.

This symposium brings together experts in the real world of infectious diseases and mathematical modelers.

Speakers show how models can be designed and analyzed so that theoretical work can have a significant effect on informing medical and public health decision-making processes.