compounds

Scientists have discovered the mechanism behind how compounds in red wine called polyphenols slow the cognitive declines of Alzheimer's.

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(University of Chicago) Scientists from three Chicago-area universities have joined forces to develop new ways of building state-of-the-art chemical libraries that will help identify new compounds for future drug development and basic biomedical research.

A series of isoprene/NOx/air irradiation experiments, carried out in both the absence and presence of SO2, were conducted to assess whether isoprene contributes to secondary organic aerosol (SOA) formation.

In the absence of SO2 , the SOA yield of 0.002 was low. However, in the presence of SO2, the SOA yield increased significantly to 0.028 and 2-methylthreitol, 2-methylerythritol and 2-methylglyceric acid were detected in the laboratory SOA samples.

(University of Michigan) The University of Michigan received $5 million from the National Institutes of Health to develop the world's leading resource of high-quality experimental data sets of drug-making compounds that will ultimately take computer-aided drug design to a new level.

This project summary describes an improved approach for estimating route-specific exposures and tissue doses for trihalomethane (THM) compounds found in drinking water.

Scientists have made a significant finding that could lead to better drugs for several degenerative diseases including Huntington's disease and Alzheimer's disease.

Compounds that block the activity of a specific enzyme prevented brain injury and greatly improved survival in fruit flies that had the same disease process found in Huntington's disease.

(Emory University) The selective gene-silencing technique called RNA interference holds promise for medicine if it can be adapted to work in humans.

Certain antibiotic compounds called fluoroquinolones enhance the effectiveness of RNA interference in cells and could reduce potential side effects.

Some of the most challenging problems in science concern the behavior of the most commonplace compound on the planet's surface -- water.

But some of the mysteries are now being unravelled by the latest analysis and imaging techniques in an unfolding story that was presented at a recent conference organized by the European Science Foundation focusing on interaction between water and other compounds at the molecular level.

Two recent studies provide a potential mechanism by which investigational anti-cancer compounds known as HDAC inhibitors specifically damage cancer cells as well as clues about possible adverse effects of these compounds -- findings with important implications for their clinical use as cancer therapies.