(University of Pittsburgh Schools of the Health Sciences) Pittsburgh researchers report that alterations in a molecular brain pathway activated by marijuana, called cannabinoid 1 receptor, may contribute to the cognitive symptoms of schizophrenia, suggesting possible new drug targets that could help to improve functioning and memory in people with the mental illness.
Expression of CB1R, the site of action of the main chemical ingredient of marijuana, is significantly reduced in the brains of individuals with schizophrenia.
cognitive symptomsSchizophrenia linked to dysfunction in molecular brain pathway a...EurekAlert! - Chemistry, Physics and Materials Sciences Sun, 07/06/2008 - 22:00
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