clinical trials

Why aren't pregnant women included in most clinical trials? That's the question posed by leading bioethicists, who say it's time to confront the challenges that have led to the exclusion of pregnant women from important research that could positively impact maternal and fetal health.

Vaginal microbicides currently in clinical trials may be the only weapon that will protect women against infection from HIV.

Yet, under likely circumstances, these microbicides may be of more benefit to men than women, according to a new UCLA AIDS Institute study.

Could injecting a gene into a patient with severe heart failure reverse their disabling and life-threatening condition?

Physician-scientists are setting out to answer that question in a first-ever clinical trial of gene therapy to treat severe heart failure.

(HCIL) Two new clinical trials presented by Calpis Co., Ltd. at the American Society of Hypertension Twenty-Third Annual Scientific Meeting and Exposition in New Orleans show that the milk-derived dietary supplement AmealPeptide reduces blood pressure in hypertensive patients.

Recent clinical trials indicate that estrogen replacement therapy may increase the risk of cardiovascular disease.

A new study in mice has examined whether adverse effects of ERT are related to the doses used. Researchers found that moderate and high doses of ERT increased problems in the kidney and heart.

The results suggest that ERT dosage may be an important determinant in a woman's overall health.

Recent clinical trials indicate that estrogen replacement therapy may increase the risk of cardiovascular disease.

A new study in mice has examined whether adverse effects of ERT are related to the doses used. Researchers found that moderate and high doses of ERT increased problems in the kidney and heart.

The results suggest that ERT dosage may be an important determinant in a woman's overall health.

A groundbreaking discovery about how molecules work sheds new light on a Nobel-Prize winning theory from a decade ago.

New work imparts the need for caution in current clinical trials using the technology, as it may have potentially harmful effects on subjects.

Hospitals that participate in clinical trials appear to provide better care for patients with heart attacks or other acute heart events and have lower death rates than hospitals that do not participate in clinical trials, according to a new report.

About one-fourth to one-half of new cancer treatments that reach assessment in phase 3 randomized clinical trials are eventually proven successful, according to a new report.

Overall, 30 percent of the trials had statistically significant results; in 80 percent of those cases, new treatments were superior to established protocols.

A new drug, soon to enter clinical trials for malaria treatment, also appears to be 10 times more effective than the key medicine used to toxoplasmosis, which infects nearly one-third of all humans.

The drug, known as JPC-2056, is extremely effective in mice against Toxoplasma gondii, the parasite that causes toxoplasmosis, without toxicity.