(University of Chicago) The moment that James Pilcher has been waiting for since 1994 will arrive at 1:30 a.m. CDT on Wednesday, Sept. 10, when the world's largest scientific instrument is scheduled to begin operation.Pilcher is among six University of Chicago faculty members and more than a dozen research scientists and students, both graduate and undergraduate, who have contributed to the design and construction of the Large Hadron Collider in Geneva, Switzerland.