cellular mechanism

A mixture of seven antiandrogens induces reproductive malformati...

Recent Science Inventory records from the EPA  Thu, 11/20/2008 - 14:29

To date, regulatory agencies have not considered conducting cumulative risk assessments for mixtures of chemicals with diverse mechanisms of toxicity because it is assumed that the chemicals will act independently and the individual chemical doses are not additive.

However, this assumption is not supported by new research addressing the joint effects of chemicals that disrupt reproductive tract development in the male rat by disrupting the androgen signalling pathway via diverse mechanisms of toxicity [i.e. androgen receptor (AR) antagonism in the reproductive tract vs.


 

New Cellular Mechanism That Will Significantly Advance Vaccine D...

ScienceDaily  Wed, 06/18/2008 - 13:15

Scientists have discovered a new, previously unknown mechanism in how the body fights a virus. The finding runs counter to traditional scientific understanding of this process and will provide scientists a more effective method for developing vaccines.


 

LIAI researchers discover new cellular mechanism that will signi...

EurekAlert! - Chemistry, Physics and Materials Sciences  Sun, 06/15/2008 - 22:00

(La Jolla Institute for Allergy and Immunology) La Jolla Institute for Allergy & Immunology scientists have discovered one for the textbooks.

Their finding, reported Friday in the scientific journal Immunity, illuminates a new, previously unknown mechanism in how the body fights a virus.

The finding runs counter to traditional scientific understanding of this process and will provide scientists a more effective method for developing vaccines.


 

New study reveals brain cell mechanism of alcohol dependence

EurekAlert! - Chemistry, Physics and Materials Sciences  Tue, 05/27/2008 - 22:00

(Society for Neuroscience) A study released today reveals a cellular mechanism involved in alcohol dependence.

The study, in the May 28 issue of The Journal of Neuroscience, shows that gabapentin, a drug used to treat chronic pain and epilepsy, reduces alcohol intake in alcohol-dependent rats by normalizing chemical communication between neurons, which is altered by chronic alcohol abuse.


 

Salt-tolerant Gene Found In Simple Plant Nothing To Sneeze At

ScienceDaily  Tue, 04/08/2008 - 00:00

Whether a plant withers unproductively or thrives in salty conditions may now be better understood by biologists.

The cellular mechanism that controls salt tolerance has been found in the arabidopsis plant. Complex-N-glycan, a carbohydrate linked to a protein in plant cells, was previously thought to have no helpful function for plant growth and to cause certain allergies in humans, said one of the researchers.