cell replication

This works extends the 2-stage cancer modeling of tumor incidence in formaldehyde-exposed rats carried out at the CIIT Centers for Health Research.

We modify key assumptions, evaluate the effect of selected uncertainties, and develop confidence bounds on parameter estimates.

The broad features of our model are similar to the CIIT effort and the related input data were obtained from that work.

Our approach differs from that work due to the following. (1) We develop non-homogeneous solutions to the 2-stage MVK cancer model.

This replaces the homogeneous solutions due to Hoogenveen et al.

A discovery from Stanford researchers is the first to directly link the notorious members of the retinoblastoma family of proteins to the cellular production factories responsible for churning out all the blood and immune cells in the body.

Researchers have identified a gene that is responsible for the division and movement of marrow-derived, blood-forming stem cells, a finding that could have major implications for the future of bone marrow and blood cell transplantation.

Scientists have observe for the first time in living cells a key step in the creation of adenine and guanine, two of the four building blocks that comprise DNA.

Also called purines, the building blocks are essential for cell replication. The findings, published in Science, could lead to new cancer treatments that prevent cancer cells from replicating by interfering with their abilities to make purines.