cancer growth

A new study suggests a possible role for nicotine in breast tumor development and metastases.

(American Association for Cancer Research) A study published in Cancer Research, a journal of the American Association for Cancer Research, suggests a possible role for nicotine in breast tumor development and metastases.

Researchers have shown a mechanism that explains how two essential components of human telomerase -- normally active only in early prenatal development but turned back on during cancer growth -- are "recruited" from distinct sites in the cell to the telomere, an area at the end of a chromosome that normally protects it from destruction.

(University of Georgia) Researchers at the University of Georgia's Franklin College of Arts and Sciences have shown a mechanism that explains how two essential components of human telomerase -- normally active only in early prenatal development but turned back on during cancer growth -- are "recruited" from distinct sites in the cell to the telomere, an area at the end of a chromosome that normally protects it from destruction.

It is widely believed that tumor angiogenesis and cancer growth critically depend on circulating endothelial precursor cells, mobilized from the bone marrow.

A new study now suggests that a stem cell type supposed to be crucial for blood vessel formation and cancer growth does not actually exist.

A restricted-calorie diet inhibited the development of precancerous growths in a two-step model of skin cancer, reducing the activation of two signaling pathways known to contribute to cancer growth and development.

A small RNA molecule, known as let-7 microRNA (miRNA), substantially reduced cancer growth in multiple mouse models of lung cancer.

This new work demonstrates that let-7 inhibits the growth of lung cancer cells in culture and in lung tumors in mice.

They also showed that let-7 can be applied as an intranasal drug to reduce tumor formation in a RAS mouse model lung cancer.