brain tumor

New data have characterized a molecular pathway underlying low-grade forms of a type of brain tumor known as an astrocytoma.

The authors therefore suggest that therapeutics targeting this pathway might provide a new approach to treating individuals with low-grade atrocytomas.

Researchers have identified a potential new neuronal tumor suppressor. Neural crest-derived tumors include neuroblastomas and medulloblastomas, which are the most common malignant pediatric solid tumors, as well as paragangliomas (relatively rare tumors of the sympathetic nervous system) and melanomas, the deadliest form of skin cancer.

No therapy, other than invasive surgery aiming at a single tumor and which may not eradicate the full extent of the tumors, currently exists.

By developing drug therapies will provide patients with a viable, non-invasive alternative.