A new study suggests that acute myeloid leukemia (AML) may occur in part because abnormally low levels of a particular microRNA result in the over-activity of two genes important to the disease.
The research involved 85 patients with AML and gene mutations called NPM1, seen in about one-third of adult AML cases, and FLT3.
The findings suggest new therapeutic targets for treating the disease and should improve the understanding of AML.
acute myeloid leukemiaLow Micro-RNA Level Linked To High Gene Activity In AMLScienceDaily Mon, 03/10/2008 - 22:00
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