acute lymphoblastic leukemia

The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia could offer a pathway to predicting such resistance and treatments to overcome it, according to a St.

Jude Children's Research Hospital study.

Researchers have discovered evidence that a series of genetic mutations work together to initiate most cases of an aggressive and often-fatal form of acute lymphoblastic leukemia.

In a new study published in PLoS Medicine, William Evans of St. Jude Children's Research Hospital, Memphis, and colleagues provide new insight into resistance to the widely-used cancer drug methotrexate in patients with acute lymphoblastic leukemia, the most common cancer in children.

The dramatic increase that has occurred in the cure rate for children with acute lymphoblastic leukemia will be difficult to replicate in older patients without considerable additional research, according to a new article.

Research aimed at understanding the success in treating pediatric acute lymphoblastic leukemia combined with molecular science could help clinicians treat adolescents and adults with the disease.

Strawberries, grapes, blueberries and some familiar seasonings like rosemary contain compounds that can--in test tubes--kill cells of a childhood cancer.

Molecular biologists are working to understand exactly how the powerful plant chemicals fight the disease known as acute lymphoblastic leukemia.

Investigations provide some new clues about how phytochemicals attack cancer cells. Phytochemicals interfere with the orderly operations of mitochondria, the miniature energy-producing power plants inside cells.