Multiple lethal pathogens such as H5N1 avian flu trigger acute lung injury with a high death rate. Scares of an epidemic have led to an increasing interest in understanding the molecular mechanisms that lead to this condition.
A team of scientists led by Josef Penninger and Yumiko Imai of IMBA, Vienna, have identified oxidative stress and innate immunity as a common pathway that controls the severity of ARDS.
The journal Cell reports this week.
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