Investigation Of Prion Folding On Cell Membranes

Courtesy ScienceDaily  Mon, 08/11/2008 - 22:00

Abnormally folded proteins cause a number of illnesses such as the Creutzfeldt-Jacob Disease, BSE (bovine spongiform encephalopathy) and Alzheimer’s.

It is still unknown why this misfolding occurs. The first stages of folding and the onset of the aggregation of the proteins, the so-called oligomerisation, appear to be decisive for pathogenesis.


 

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