Herpes drug inhibits HIV replication, but with a price

Courtesy EurekAlert! - Chemistry, Physics and Materials Sciences  Wed, 11/05/2008 - 23:00

(American Society for Biochemistry and Molecular Biology) The anti-herpes drug acyclovir can also directly slow down HIV infection by targeting the reverse transcriptase enzyme, researchers report.

This beneficial effect does pose a risk though, as HIV-infected cells treated with acyclovir promote the emergence of multi-drug resistant HIV variants.

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