Insulin-like growth factor has to date been shown to stimulate the growth and proliferation of cells, and recently was found to affect the shape and growth rate of nerve axons.
Now, UC Berkeley neuroscientist John Ngai and colleagues have shown that IGF also controls the direction of axon growth as axons stretch from the nose's odor detectors to the brain's olfactory bulb.
Axon guidance represents a new role for IGF in development.
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