Gene Mutations Tied To Immune Comeback During Therapy For HIV-1

Courtesy ScienceDaily Wed, 04/02/2008 - 07:00

A new study provides compelling evidence that two genes are linchpins in defining the course of immune restoration in HIV-positive individuals undergoing virus-suppressing therapy.

The findings explain why some subjects' immune systems fail to have a sustained immune comeback, despite suppression of HIV-1 replication by highly active antiretroviral therapy (HAART), while others' immune systems roar back.

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