Function Of Molecular Switch Pinpointed In Severe Congenital Neu...

Courtesy ScienceDaily Mon, 03/10/2008 - 01:00

Researchers cleared an important hurdle to clarifying the molecular mechanics behind Severe Congenital Neutropenia, a deadly disease characterized by a deficiency of neutrophils -- mature white blood cells important to fighting infection and disease.

A genetic mutation found in humans with SCN blocks neutrophil development in mouse bone marrow cells, providing a way to more effectively study the disease.

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