The EPA ToxCast Program: Developing Predictive Bioactivity Signa...

Courtesy Recent Science Inventory records from the EPA  Mon, 11/10/2008 - 14:33

There are tens of thousands of chemicals used in the environment for which little or no toxicology information is known.

Current testing paradigms that use large numbers of animals to perform in vivo toxicology are too slow and expensive to apply to this large number of chemicals.

An alternative approach is to use high throughput in vitro methods to analyze the behavior of many environmental chemicals in a rapid and cost-effective manner.

The outcome of such experiments will include mechanistic...

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