Development of normal human colon cell cultures to identify prio...

Courtesy Recent Science Inventory records from the EPA  Tue, 11/03/2009 - 13:43

Epidemiological studies have linked the consumption of chlorinated surface waters to an increased risk of colorectal cancer.

At present ~600 DBPs have been identified as the major disinfectants and these represent only a fraction of the total organic carbon recovered.

An in-depth mechanism-based structure activity relationship analysis identified 50 unregulated DBPs with little or no toxicological data.

In order to prioritize unregulated DBPs from this list for testing, we are developing an in vitro system that identifies DBPs with the...

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